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Parity and Stroke: Racial Differences Examined
J Stroke Cerebrovasc Dis; ePub 2016 Nov 8; Vladutiu, et al
No statistically significant associations were observed between parity and stroke risk in a diverse cohort of US women, a recent study found. Researchers assessed the association between parity and incident stroke among 7,674 white and 6,280 black women, aged ≥45, and enrolled in the REasons for Geographic and Racial Differences in Stroke Study from 2003 to 2007. They found:
- At baseline, 12.7% of white women and 16.2% of black women reported 1 live birth, while 8.2% and 19.0%, respectively, reported 5 or more live births.
- Mean follow-up time was 7.5 years (standard deviation=2.8); there were 447 incident strokes.
- Among white women, those with 5 or more live births had a higher stroke risk than those with 1 live birth. However, the association was eliminated after adjustment for baseline characteristics.
- For black women, those with 5 or more live births had the highest stroke risk compared with those with 1 live birth, but the association was attenuated and no longer statistically significant after adjustment for confounders.
Vladutiu CJ, Mayer ML, Malek AM, et al. Racial differences in the association between parity and incident stroke: Results from the REasons for Geographic and Racial Differences in Stroke Study. [Published online ahead of print November 8, 2016]. J Stroke Cerebrovasc Dis. doi:10.1016/j.jstrokecerebrovasdis.2016.10.010.