Clinical Edge Journal Scan

TVUS + SE presents a specific and sensitive technique for differential diagnosis of uterine fibroids and adenomyosis


 

Key clinical point: Diagnostic specificity and sensitivity were high enough to distinguish uterine fibroids (UFs) from adenomyosis when a combination of transvaginal ultrasound (TVUS) and strain ratio (SR) elastography (SE) techniques was implemented.

Major finding: Patients with histologically confirmed UFs vs. those with adenomyosis had a significantly lower mean (5.20±1.81 vs 11.42±1.87) and max (5.78±2.08 vs 13.43±4.10) SR values (both P < .001). Diagnostic sensitivity (90.56% vs. 86.2%) and specificity (96.15% vs 91.37%) were higher for UFs than adenomyosis.

Study details: Findings are from a pilot, prospective study including 79 patients who underwent hysterectomy for suspicion of either UF (n=53) or adenomyosis (n=25), diagnosed on the basis of 2-dimensional TVUS in combination with SE findings.

Disclosures: This study did not receive any funding. The authors declared no conflict of interests.

Source: Săsăran V et al. J Pers Med. 2021 Aug 23. doi: 10.3390/jpm11080824 .

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