DANA POINT, CALIF. – When is someone too young for antiaging procedures with cosmetic fillers or laser resurfacing?
Chronologic age "is somewhat irrelevant," in the opinion of Dr. Elizabeth L. Tanzi, codirector of the Washington (D.C.) Institute of Dermatologic Laser Surgery. "I’m looking at dermatologic age, with a critical evaluation of [a patient’s] need," she said at a meeting sponsored by SkinCare Physicians and Northwestern University.
Dr. Elizabeth L. Tanzi
Dr. Tanzi noted that genetics also plays a role in how each person’s skin ages over time. "Some people have inherited facial expressions," she explained. "They may get hyperdynamic movement in certain parts of their face and develop wrinkles much earlier than you would anticipate. Environmental exposure clearly plays a large role. Excessive ultraviolet exposure, growing up with outdoor sporting activities, tanning bed use, or poor habits such as smoking are going to lead to an accelerated aging process," she said.
The importance of establishing realistic patient expectations starts with the first office consultation, when clinicians emphasize that "we can slow down the signs of aging on your skin, but we cannot stop the process completely," said Dr. Tanzi, who is also an assistant professor of dermatology at George Washington University Medical Center, Washington. "I think it’s more important to talk about looking youthful, energetic, and vibrant, not necessarily looking young, because we may be inadvertently delivering the wrong message – that all aging is preventable if treatments are started early enough – and that sets the stage for unrealistic expectations."
Encouraging sun protection behaviors is sensible, and "most dermatologists realize that you can use neuromodulators and fillers strategically early on," Dr. Tanzi said. "But the idea of using fractionated laser resurfacing treatments to promote improved skin function is intriguing to me. We know we can improve the skin cosmetically through a series of fractional laser resurfacing treatments. But can we functionally improve the skin as it’s aging?" she questioned.
Cutting-edge research suggests that may be the case. In 2012, Dan F. Spandau, Ph.D., and his colleagues (J. Invest. Dermatol. 2012;132:1591-6) published data showing that dermal wounding procedures such as fractional resurfacing can "wake up senescent dermal fibroblasts to produce more insulin-like growth factor-1 (IGF-1), which helps the epidermis ward off the damaging effects of UVB on the skin," Dr. Tanzi said. In that case, she continued, "should we be recommending fractional resurfacing as part of a healthy antiaging routine? If so, at what age? These are exciting developments that need additional research to help guide new treatment protocols."
Although she is enthusiastic about preventing some signs of aging and helping patients maintain a youthful appearance, Dr. Tanzi expressed some concerns. "If we are not careful, we could be setting ourselves up for an expectation of being able to stop the aging process, and this can be a slippery slope, especially for women," she said. "Especially when it comes to fillers and neuromodulators, if not done judiciously they can lead to a very artificial look which, ironically, makes women look much older," Dr. Tanzi said. "As thoughtful physicians, it’s important to keep perspective and guide patients to know when enough is enough [in terms of procedures]," she added.
Dr. Tanzi disclosed that she is a consultant for Cynosure/Palomar, Lumenis, and other companies.