Evidence-Based Reviews

Bipolar disorder or borderline personality disorder?

Author and Disclosure Information

 

References

Several factors might make clinicians reluctant to diagnose BPD, or bias them to diagnose BD more frequently. These include a lack of familiarity with the diagnostic criteria for BPD, the phenotypical resemblance between BP and BPD, or even concerns about the stigma and negative implications that are associated with a BPD diagnosis.32,37,38

Whereas BD is currently perceived as a condition with a strong biological basis, there are considerable misconceptions regarding BPD and its nature.4-6,22,26 As a consequence, individuals with BPD tend to be perceived as “difficult-to-treat,” “uncooperative,” or “attention-seeking.” These misconceptions may result in poor clinician-patient relationships, unmet clinical and psychiatric needs, and frustration for both clinicians and patients.37

Through advances in biological psychiatry, precision medicine may someday be a part of psychiatric practice. Biological “signatures” may eventually help clinicians in diagnosing and treating psychiatric disorders. Presently, however, rigorous history-taking and comprehensive clinical assessments are still the most powerful tools a clinician can use to accomplish these goals. Finally, destigmatizing psychiatric disorders and educating patients and clinicians are also critical to improving clinical outcomes and promoting mental health in a compassionate and empathetic fashion.

Bottom Line

Despite the phenotypical resemblance between bipolar disorder (BP) and borderline personality disorder (BPD), the 2 are independent conditions with distinct neurobiological and psychopathological underpinnings. Clinicians can use a rigorous assessment of pathological personality traits and characterization of symptoms, such as onset patterns, clinical course, and phenomenology, to properly distinguish between BP and BPD.

Related Resources

Pages

Recommended Reading

Inflammatory markers may start in later stages of bipolar disorder
MDedge Psychiatry
Virtual dark therapy tames manic episodes
MDedge Psychiatry
The challenges of caring for a physician with a mental illness
MDedge Psychiatry
Premature mortality across most psychiatric disorders
MDedge Psychiatry
The 84-year-old state boxing champ: Bipolar disorder, or something else?
MDedge Psychiatry
Distinct mood, apathy profiles found in bipolar disorder patients
MDedge Psychiatry
Lithium drug interactions not quite as bad as imagined
MDedge Psychiatry
Regional brain activation lower in bipolar disorder patients after multiple manic episodes
MDedge Psychiatry
#MomsNeedToKnow mental health awareness campaign set to launch
MDedge Psychiatry
Increased Parkinson’s disease risk seen with bipolar disorder
MDedge Psychiatry