In the survey I mentioned at the beginning of this editorial, 60.5% of responders predicted that the DSM-6 (approximately a decade from now) will contain laboratory tests for psychiatric diagnosis. They may very well be right!
Table
Biomarkers for schizophrenia
| α-1 antitrypsin | IL-7 |
| Apolipoprotein A1 | IL-10 |
| Apolipoprotein A2 | IL-11 |
| Apolipoprotein B | IL-17 |
| Apolipoprotein CI | KIM-1 |
| Apolipoprotein H | LH |
| β-2 microglobulin | MCP-2 |
| Betacellulin | MDC |
| BDNF | MIF |
| CA | MIP-1 α |
| Calbindin | MMP-2 |
| Cancer antigen 125 | Prolactin |
| CD5L | Prostatic acid phosphatase |
| Complement 3 | PYY |
| Cortisol | Serum amyloid P |
| CTGF | Sortilin |
| EGFR | Testosterone |
| Endothelin 1 | Thrombopoietin |
| Ferritin | TIMP 1 |
| Fetuin A | TNF R 2 |
| FSH | Trail R3 |
| Haptoglobin | Transferrin |
| ICAM1 | TSH |
| IgA | VEGF |
| IgM | Vitronectin |
| IL-6 receptor | |
| BDNF: brain-derived neurotrophic factor; CD5L: CD5 molecule-like; CTGF: connective tissue growth factor; EGFR: epidermal growth factor receptor; FSH: follicle-stimulating hormone; ICAM1: intercellular adhesion molecule 1; IgA: immunoglobulin A; IgM: immunoglobulin M; IL-6 receptor: interleukin 6 receptor; IL-7: interleukin 7; IL-10: interleukin 10; IL-11: interleukin 11; IL-17: interleukin 17; KIM-1: kidney injury molecule-1; LH: luteinizing hormone; MCP-2: monocyte chemotactic protein 2; MDC: mature dendritic cell; MIF: macrophage migration inhibitory factor; MIP-1 α: macrophage inflammatory protein 1 α; MMP-2: matrix metalloproteinase 2; PYY: peptide YY; TIMP 1: TIMP metallopeptidase inhibitor 1; TNF R 2: tumor necrosis factor receptor 2; TSH: thyroid-stimulating hormone; VEGF: vascular endothelial growth factor Source: Reference 3 | |