Clinical Edge Journal Scan

Increased risk of RA in patients with endometriosis


 

Key clinical point: Patients with endometriosis are at a significantly higher risk of developing rheumatoid arthritis (RA).

Major finding: The risk of RA was significantly higher in patients with endometriosis (adjusted hazard ratio [aHR], 1.75; 95% confidence interval [CI], 1.27-2.41), those aged 45 years or older (aHR, 1.50; 95% CI, 1.06-2.13), and those with autoimmune disease (aHR, 6.99; 95% CI, 2.84-17.21).

Study details: This 13-year Taiwanese population-based study included 14,463 women with and 14,463 women without endometriosis who were propensity score-matched by age, comorbidities, corticosteroids, nonsteroidal anti-inflammatory drugs, and hormonal medications.

Disclosures: The study was supported by the Chung Shan Medical University’s DryLab Team and grants awarded to Chung Shan Medical University. The authors declared no conflicts of interest.

Source: Xue YH et al. Rheumatology (Oxford). 2020 Dec 17. doi: 10.1093/rheumatology/keaa784 .

Recommended Reading

Oral glucocorticoids plus PPIs raise osteoporotic fracture risk in patients with RA
MDedge Rheumatology
RA: Depression tied to greater disease activity and pain
MDedge Rheumatology
Inflammation of juxta-articular soft tissues could be an early feature of RA
MDedge Rheumatology
Clinical Edge Journal Scan Commentary: RA Jan 2021
MDedge Rheumatology
Arthritis drugs ‘impressive’ for severe COVID but not ‘magic cure’
MDedge Rheumatology
Lung disease raises mortality risk in older RA patients
MDedge Rheumatology
Hydroxychloroquine use not linked to heart failure risk in patients with RA
MDedge Rheumatology
Elevated disease activity, cytokine levels linked to diabetes risk in RA
MDedge Rheumatology
CVD and CV risk factors linked to increased dementia risk in patients with RA
MDedge Rheumatology
Efficacy of filgotinib in patients with RA with limited or no methotrexate exposure
MDedge Rheumatology