Clinical Edge Journal Scan

No clinically relevant increase in mortality in patients with PsA


 

Key clinical point: Psoriatic arthritis (PsA) was not associated with a significant increase in risk for all-cause mortality in the more recent era between 2003 and 2018. Moreover, the major causes of death in PsA were not different than those commonly reported in the general population.

Major finding: The number of deaths was similar in PsA and control groups (8.9% and 7.9%, respectively), and the association between PsA and a higher risk for all-cause mortality was not significant (hazard ratio, 1.02; 95% confidence interval, 0.90-1.15). In the general population, malignancy (26.0%) and ischemic heart disease (15.8%) were the leading causes of death in patients with PsA.

Study details: Findings are from an analysis of a cohort of 5,275 adults newly diagnosed with PsA between 2003 and 2018, matched with 21,011 control participants and followed for 7.2 ±4.4 years.

Disclosures: The study did not report any source of funding. No conflict of interests was reported.

Source: Haddad A et al. J Rheumatol. 2021 Jul 15. doi: 10.3899/jrheum.210159 .

Recommended Reading

Western diet promoted skin, joint inflammation in preclinical study
MDedge Rheumatology
Psoriatic arthritis health care costs continue to rise over time
MDedge Rheumatology
Bimekizumab approved in Europe for psoriasis treatment
MDedge Rheumatology
PsA: Guselkumab demonstrates clinically meaningful and sustained improvement in fatigue
MDedge Rheumatology
Burden of psoriasis is mild in early PsA but impacts HRQoL
MDedge Rheumatology
Treating skin with biologics may reduce risk of developing PsA in patients with psoriasis
MDedge Rheumatology
JAK inhibitors safe and effective over placebo for PsA
MDedge Rheumatology
Secukinumab provides low radiographic progression over 2 years in patients with PsA
MDedge Rheumatology
Secukinumab effective for PsA, with high patient satisfaction in the real world
MDedge Rheumatology
Oligoarticular PsA similar to polyarticular PsA with few exceptions
MDedge Rheumatology