Article

Premenopausal women with RA at higher risk for diastolic dysfunction


 

Key clinical point: Premenopausal women with rheumatoid arthritis (RA) had a significantly higher risk for diastolic dysfunction, and early screening may help prevent future cardiovascular events.

Major finding: Patients with RA had a significantly higher incidence of diastolic dysfunction (odds ratio [OR] 2.18; P = .020), with the risk being higher in women aged between 30 and 49 years vs. control participants of the same age (OR 3.54; 95% CI 1.27-9.85).

Study details: This study involved 61 premenopausal women with RA without any history of hypertension matched with 107 control participants.

Disclosures: No funding or financial conflict of interests was reported.

Source: Kim GH et al. Arthritis Res Ther. 2021 (Sep 24);23:247. doi: 10.1186/s13075-021-02629-1.

Recommended Reading

U.S. arthritis prevalence continues steady rise; activity limitations grow more rapidly
MDedge Rheumatology
Tramadol linked to higher risk of mortality, compared with codeine
MDedge Rheumatology
Better COVID-19 outcomes confirmed in TNF inhibitor users
MDedge Rheumatology
Low lean mass and sarcopenic obesity more prevalent in RA
MDedge Rheumatology
RA: No effect of treatment switch from reference adalimumab to biosimilar PF-06410293
MDedge Rheumatology
No link between statin use and RA occurrence
MDedge Rheumatology
Use of bDMARDs lowers total knee and hip replacement risk in RA
MDedge Rheumatology
RA: Discontinuation of denosumab leads to reversal of treatment gains
MDedge Rheumatology
No effect of bDMARD treatment on risk for cancer recurrence or new cancer in RA
MDedge Rheumatology
Sarilumab monotherapy as effective as sarilumab + methotrexate combo in RA
MDedge Rheumatology