Clinical Edge Journal Scan

Meta-analysis evaluates degree of skin involvement in patients with PsA vs only psoriasis


 

Key clinical point: Patients with psoriasis and concurrent psoriatic arthritis (PsA) reported more extensive skin disease than patients with only psoriasis, with psoriasis severity being significantly associated with higher odds of concurrent PsA.

Major finding: Body surface area scores were significantly higher in patients with psoriasis and concurrent PsA vs patients with only psoriasis (mean difference 5.31; 95% CI 1.78-8.83), with severe psoriasis being a significant predictor of concurrent PsA ( odds ratio 3.34; P < .001 ).

Study details: This was a meta-analysis of 29 studies including adult patients with psoriasis with or without concurrent PsA or adult patients with psoriasis who developed PsA.

Disclosures: This study did not receive any funding. JM Laar declared receiving research grants and honoraria from several sources.

Source: Pouw JN et al. Do patients with psoriatic arthritis have more severe skin disease than patients with psoriasis only? A systematic review and meta-analysis. Dermatology. 2022 (May 12). Doi: 10.1159/000524231

Recommended Reading

Upadacitinib earns FDA approval for ankylosing spondylitis 
MDedge Rheumatology
Reduced-frequency methotrexate monitoring causes no harm
MDedge Rheumatology
‘Shielding’ status provides best indicator of COVID-19 mortality in U.K. arthritis population
MDedge Rheumatology
Severe infections often accompany severe psoriasis
MDedge Rheumatology
FDA approves topical tapinarof for plaque psoriasis
MDedge Rheumatology
Improved outcomes with 6-month secukinumab use in PsA
MDedge Rheumatology
Sex and BMI affect response to systemic PsA therapy
MDedge Rheumatology
PsA: Real-world efficacy, safety, and retention rate of secukinumab
MDedge Rheumatology
Site of infection linked to PsA onset regardless of pathogen
MDedge Rheumatology
Osteophytes are the most common lesions in PsA patients receiving bDMARD
MDedge Rheumatology