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Progression of Cartilage Lesions in Hip Osteoarthritis

Osteoarthr Cartilage; ePub 2016 Mar 10; Gallo, Wyatt, et al

Publish date:: March 21, 2016

T_1ρ and T₂ relaxation parameters are associated with morphological cartilage degeneration at 18 months and may serve as potential imaging biomarkers for progression of cartilage lesions in hip osteoarthritis (OA). This according to 3T MRI studies of the hip in 54 participants without evidence of severe OA at baseline who were followed-up at 18 months. Researchers found:

• Significantly higher baseline T_1ρ and T₂ values were seen in hip OA progressors vs nonprogressors, especially in the postersuperior and anterior aspects of the femoral cartilage.

• Logistic regression showed that higher baseline T_1ρ and T₂ values in the femoral cartilage were significantly associated with progression of femoral cartilage lesions at 18 months.

Citation: Gallo MC, Wyatt C, Pedoia V, et al. T_1ρ and T₂ relaxation times are associated with progression of hip osteoarthritis. [Published online ahead of print March 10, 2016]. Osteoarthr Cartilage. doi:10.1016/j.joca.2016.03.005.

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