Lupus & Connective Tissue Diseases
From the Journals
Mycophenolate, cyclophosphamide found equal as induction therapy in pediatric lupus nephritis
The study is the largest to date investigating induction treatments for proliferative lupus nephritis in JSLE.
From the Journals
Rituximab does not improve fatigue symptoms of ME/CFS
Results from the phase 3 RituxME trial found no difference in fatigue score symptoms after 24 months.
Conference Coverage
FDA panel calls for changes to breast implant rupture screening
The advisory panel seemed the current implant screening recommendation using MRI “useless.” They urged the adoption of ultrasound as a more...
Conference Coverage
FDA panel leans toward more robust breast implant surveillance
SILVER SPRING, MD. – Amid concern over two breast implant complications – anaplastic large cell lymphoma and autoimmune symptoms – an FDA panel...
Conference Coverage
Industry-funded rheumatology RCTs are higher quality
MAUI, HAWAII – An analysis of 20 years of rheumatology clinical trials.
From the Journals
Sjögren’s syndrome risk increases with infections
The syndrome was almost three times more likely with infection history plus certain antibodies.
From the Journals
Socioeconomic status affects scleroderma severity in African Americans
African American scleroderma patients have more severe disease, compared with other races, but not when controlling for socioeconomic status.
From the Journals
Resistant hypertension hits SLE patients hard
Higher risk for resistant hypertension goes hand in hand with higher mortality.
Conference Coverage
BTK inhibitor calms pemphigus vulgaris with low-dose steroids
WASHINGTON – PRN1008 blocks BTK receptors on B cells, thus forestalling the B-cell mediated inflammatory cascade.
Feature
Vagus nerve stimulation for rheumatology? Maybe
Targeting many cytokines at once.
From the Journals
Belimumab data out to 13 years show continued safety, efficacy
Continuation study describes longest treatment data available for belimumab.