Lupus & Connective Tissue Diseases
From the Journals
Renal transplant improves survival in lupus nephritis patients
Transplant conferred a 70% reduction in overall death risk in patients with end-stage renal disease due to lupus nephritis.
From the Journals
MMF proves viable as alternative option in moderate ANCA-associated vasculitis
Mycophenolate mofetil is a good option, especially if relapse risk is low.
From the Journals
Anticoagulation shows promise in concurrent lupus nephritis, thrombotic microangiopathy
Results come from the largest multicenter cohort study in these patients.
From the Journals
Aspirin appears underused to prevent preeclampsia in SLE patients
Approximately a quarter of pregnant women with lupus took aspirin, although half had at least one traditional preeclampsia risk factor.
From the Journals
Tofacitinib tackles cutaneous sarcoidosis
Patient given JAK inhibitor showed clinical and histologic disease remission of sarcoidosis after failing other treatments.
Conference Coverage
New insight gained into natural history of interstitial pneumonia with autoimmune features
CHICAGO – This idiopathic interstitial lung disease subtype is at high risk to progress to systemic rheumatic disease.
Conference Coverage
Drug-drug interactions in rheumatology patients on PPIs: An underappreciated problem?
CHICAGO – Reduced stomach acidity alters absorption of JAK inhibitors and other oral antirheumatic drugs.
Conference Coverage
Novel SSc classification scheme aims to improve risk stratification
CHICAGO – The scheme combines autoantibody specificity and extent of skin involvement.
From the Journals
Increased cancer risk in dermatomyositis has temporal limits
Conference Coverage
Combination immunotherapy ups survival in ILD patients with anti-MDA5–positive dermatomyositis
But cytomegalovirus reactivation and other opportunistic infections must be monitored.
From the Journals
Composite screening measures advocated for asymptomatic PAH
Employing novel screening algorithms such as DETECT and ASIG aid in early detection of pulmonary arterial hypertension.