Lupus & Connective Tissue Diseases
From the Journals
Anti-BDCA2 antibody meets primary endpoint in phase 2 cutaneous lupus trial
In the phase 2 study, improvements in the Cutaneous Lupus Erythematosus Disease Area and Severity Index–Activity score were seen in patients...
News from the FDA/CDC
FDA approves belimumab for children with lupus nephritis
Children with lupus-related kidney damage can now receive the B cell–reducing therapy that adults with lupus nephritis have been able to get for...
Feature
Methotrexate’s impact on COVID-19 vaccination: New insights made
New studies assess patients with various immune-mediated inflammatory diseases to determine the risks and benefits of pausing methotrexate after...
Latest News
Think of pediatric morphea as a systemic, chronic disease, expert advises
Predictors of poor quality of life include female sex and involvement of hands and feet.
Feature
No more ‘escape hatch’: Post Roe, new worries about meds linked to birth defects
Physicians fear that women won’t get the best treatments or will face dangerous risks.
Conference Coverage
Autoimmune disease linked to better late-stage breast cancer survival
Retrospective data hint at antitumor activity, but other explanations are possible
Conference Coverage
Deucravacitinib and orelabrutinib perform well in early lupus trials
Disease activity was reduced by treatment with either of the novel investigational agents in two separate early clinical trials, with further...
Conference Coverage
Stopping immunosuppressives in lupus nephritis isn’t noninferior to continuing
Risk of renal relapse and SLE flares was greater in patients with lupus nephritis who discontinued rather than continued immunosuppressive therapy...
Conference Coverage
Think it’s ILD? Tell it to the machines
Feature
Lupus mutation may unlock targeted drugs for patient subset
A new study provides definitive proof of one pathway that contributes to lupus, though it’s unclear how many patients with lupus are affected by...
Conference Coverage
High maternal, fetal morbidity rates in SLE pregnancies
Despite steady declines in maternal and fetal mortality among pregnant women with systemic lupus erythematosus, maternal and fetal morbidities...