Clinical Review

Causes and Rates of Unplanned Readmissions After Elective Primary Total Joint Arthroplasty: A Systematic Review and Meta-Analysis

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To address the lack of consensus on the leading reasons for readmissions after primary elective unilateral total joint arthroplasties (TJAs), we performed a systematic review and a meta-analysis to identify overall and cause-specific readmission rates.

We performed structured searches of the Medline and Cochrane databases for original reports—published between January 1982 and January 2013—on both 30- and 90-day follow-ups of unique patient populations that underwent elective primary TJA. Random-effects meta-analyses were performed to obtain pooled estimates.

For total hip arthroplasty (THA), the overall pooled readmission rate was 5.6% at 30 days and 7.7% at 90 days. For total knee arthroplasty (TKA), the overall rate was 3.3% at 30 days and 9.7% at 90 days. The leading reason for THA readmission was joint-specific at both 30 and 90 days, and the leading reason for TKA readmission was surgical site infection.

Our systematic review and meta-analysis established baseline readmission rates in the literature on primary TJA and identified the most common reasons driving readmission for TJA.


 

References

Total joint arthroplasty (TJA) is a clinically effective, cost-effective treatment for symptomatic arthritis.1,2 After TJA, patients report reduced pain, restored range of motion, high satisfaction, and ability to return to a more active lifestyle.3-7 The number of total hip arthroplasties (THAs) performed in the United States is expected to reach 572,000 by 2030, a 174% increase, and the number of total knee arthroplasties (TKAs) 3.5 million, nearly a 7-fold increase.8,9 Since 2005, the cost of THA has risen more than 4 times, to $13.43 billion, and the cost of TKA has risen more than 5 times, to $40.8 billion.8,9 Given the demand and price tag, TJA is the single largest cost in the Medicare budget.10

Given its potential to improve care and reduce costs, reducing readmission rates in the surgical setting is a priority for physicians and policymakers.11 Readmissions for TJA are highly scrutinized as a performance indicator—the Centers for Medicare & Medicaid Services (CMS) started including them in its readmissions penalty program in 2013—and were recently validated as a measure of surgical quality.12-14 Accurate assessments of readmissions after TJA are unclear, with rates ranging from 1% to 8.5% between 7 and 90 days after surgery.2,15-17 The early success of TJA as an elective (and more frequently outpatient) procedure has paradoxically translated to less tolerance for readmissions. Post-TJA complications resulting in readmission are subject to financial penalties, and there is an implicit judgment of inadequate surgical management.12

Not only is the readmission rate poorly characterized, but there is no consensus on the leading reasons for readmissions after primary elective unilateral TJAs. The range of rates, reasons, and follow-up periods reported in the literature is wide.18,19 CMS plans to monitor readmissions over 7 to 90 days after surgery (the period depends on the complication), whereas a significant portion of the orthopedic literature documents 90-day rates.19 In 2012, the Yale New Haven Health Services Corporation/Center for Outcomes Research and Evaluation prepared for CMS a comprehensive report identifying rates of post-TJA complications and readmissions.20 The report, however, is limited to US hospitals and Medicare patients and therefore may overstate the rates, given this population’s documented comorbidities and the reimbursement variations between Medicare and commercial insurance.21 Lack of consensus on readmissions after primary elective unilateral TJAs requires that we synthesize available data to answer several questions: What is the overall readmission rate 30 and 90 days after TJA? What are the primary reasons for readmission 30 and 90 days after TJA? What are the cause-specific readmission rates? We performed a systematic review and a meta-analysis to answer these questions and to add clarity to the literature in order to help guide policy.

Materials and Methods

We performed a systematic review in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.22 Two reviewers independently completed structured searches of the Medline and Cochrane Central Register of Controlled Trials databases. Search terms were: (total hip replacement OR hip arthroplasty OR total hip arthroplasty OR total knee replacement OR knee arthroplasty OR total knee arthroplasty) AND (readmission OR complication OR discharge). They updated the search June 1, 2013. Four limits were applied: publication between January 1, 1982 and December 12, 2012; human subjects only; age 19+ years; and English-language articles. Study eligibility was determined by using standardized criteria as defined by the inclusion and exclusion criteria described in 3 stages: title review, abstract review, and full-article review. The reviewers also performed ancestry searches, including searches for major review articles and bibliographies of all retrieved studies, to identify additional studies not identified in the keyword searches. Discrepancies were resolved by author consensus.

Inclusion criteria were original studies that presented level I to III evidence and that were identified in structured online searches; published in English between January 1, 1982 and December 31, 2012; involved patients older than 19 years; and reported both readmission rates and reasons at follow-up 30 or 90 days after elective primary unilateral TJA, regardless of indication. Exclusion criteria were studies that reported data from hip fracture, knee fracture, and pelvis fracture cases; those that reported data from hemiarthroplasty, Birmingham hip resurfacing procedures, other resurfacing procedures, simultaneous bilateral hip or knee arthroplasties, unicompartmental knee arthroplasty, patellofemoral arthroplasty, metastatic or bone cancer, or revision hip or knee arthroplasty; those that did not report extractable reasons for readmission; those that reported complications but did not specify readmission rates; and those that reported readmission data only from after the 90-day follow-up window. In cases in which multiple studies reported data from the same patient population, only the largest or most recent report was used.

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