Case Reports
A Rare Case of Segmental Neurofibromatosis Involving the Sciatic Nerve
Am J Orthop. 2010 May;39(5):E42-E45
Author and Disclosure Information
Aron Trocchia, MD, Alma Reyes, MD, Jon Wilson, MD, and Kimberly Les, MD
Dr. Trocchia is an Orthopaedic Resident, Department of Orthopaedics, Dr. Reyes is a Pathology Resident, and Dr. Wilson is a Pathologist, Department of Anatomical Pathology, and Dr. Les is an Orthopaedic Surgeon, Department of Orthopaedics, William Beaumont Hospital, Royal Oak, Michigan.
Segmental neurofibromatosis (NF-5) is an extremely rare variant of neurofibromatosis involving a single extremity without pathologic features beyond the midline. A case of segmental neurofibromatosis involving the sciatic nerve and its branches is presented with a detailed description of the patient’s preoperative findings plus postoperative course through 1-year follow-up. Clinical, histologic, and genetic findings are given along with a brief review of the literature on segmental neurofibromatosis. Last, treatment options and postoperative care recommendations are provided.