Investigation of the Allergenicity of a Refined Peanut Oil–Containing Topical Dermatologic Agent in Persons Who Are Sensitive to Peanuts

We determined if a topical oil containing 0.01% fluocinolone and refined peanut oil (Derma-Smoothe/FS™ topical oil), among other ingredients, included materials to which peanut-sensitive individuals were sensitized. No immediate (15-min) or delayed (72-h) skin test reactivity was demonstrated in any of the 14 subjects tested. These results suggest that this refined peanut oil–containing dermatologic preparation is safe to use, even in persons who are sensitive to peanuts.