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Hidradenitis suppurativa-associated Crohn's disease tied to increased risk of permanent stoma
Key clinical point: Hidradenitis suppurativa (HS)-associated Crohn's disease (CD) is more active, requires greater use of anti-tumor necrosis factor (anti-TNF) agents and is associated with an increased risk of permanent stoma.
Major finding: CD with HS was more active than CD without HS (56% vs. 40% years with active disease) and was associated with greater use of anti-TNF agents (39% vs. 23% years spent with anti-TNF agents; P less than .001 for both). HS was independently associated with a higher risk for permanent stoma in patients with CD (odds ratio, 6.19; P less than .001).
Study details: The data come from a retrospective study of 4,645 patients with CD (CD with HS, n=44; CD without HS, n=176).
Disclosures: No study sponsor was identified. The authors declared no conflicts of interest.
Dumont LM et al. Aliment Pharmacol Ther. 2020 Jun 11. doi: 10.1111/apt.15863.