Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Locally Recurrent LM/LMM Following Surgery
Dermatolog Surg; ePub 2017 Mar 14; Connolly, et al
The mean time to local recurrence (LR) of lentigo maligna/lentigo maligna melanoma (LM/LMM) following surgery is at least 57.5 months, underscoring the importance of long-term follow-up, a recent study found. In order to define time to LR in LM/LMM after surgical treatment, and to describe features of observed LR, researchers conducted a retrospective single-center study of consecutive patients presenting with locally recurrent LM/LMM. 649 cases of LM/LMM were reviewed; 29 (21 LM, and 8 LMM) of 41 locally recurrent cases had original histology reports and were included. They found:
- For cases presenting as primary LM, LR was also in situ in 14/21 (67%) of cases.
- 7 of 21 LM recurred as LMM.
- Of the 8 primary LMM, 3/8 (37.5%) presented with subsequent LMM and all were slightly deeper on re-excision.
Connolly KL, Hibler BP, Lee EH, et al. Locally recurrent lentigo maligna and lentigo maligna melanoma. [Published online ahead of print March 14, 2017]. Dermatolog Surg. doi:10.1097/DSS.0000000000001118.