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Subjective Factors in Genetic Skin Cancer Testing

J Am Acad Dermatol; ePub 2017 Jan 10; Fogel, et al

The decision to pursue genetic testing for skin cancer is primarily determined by subjective factors, such as anxiety and curiosity, a recent study found. Health factors, including skin cancer history, also influenced decision-making. Researchers distributed anonymous online surveys in order to assess participant health, demographics, motivations, and interest in pursuing genetic testing for skin cancer risk. 2 surveys with identical questions, but different question ordering, were used to assess the secondary objective. They found:

  • 3,783 responses (64% response rate) were received, and 85.8% desired testing.
  • Subjective factors, including curiosity, perceptions of skin cancer, and anxiety, were the most statistically significant determinants of the decision to pursue testing, followed by history of sun exposure and history of skin cancer.
  • Age and family history of skin cancer did not influence this decision.
  • Participants increasingly chose testing if first queried about health behaviors.

Citation:

Fogel AL, Jaju PD, Li S, Halpern-Felsher B, Tang JY, Sarin KY. Factors influencing and modifying the decision to pursue genetic testing for skin cancer risk. [Published online ahead of print January 10, 2017]. J Am Acad Dermatol. doi:10.1016/j.jaad.2016.11.050.