Prochlorperazine more effective than ketorolac for pediatric migraine

Q&A

J Fam Pract. 2004 June;53(6):442-450

CLINICAL QUESTION: Is ketorolac more effective than prochlorperazine in the treatment of pediatric migraine in the emergency setting?
STUDY DESIGN: Randomized controlled trial (double-blinded)
SETTING: Emergency department
SYNOPSIS: This study is a start in the right direction toward clearing up the lack of information regarding treatment of pediatric migraine in the emergency department. The investigators recruited 62 children aged 5 to 18 years presenting with migraine in either of 2 pediatric emergency departments. Migraine was defined as recurrent headache with at least 3 of the following symptoms: an aura; unilateral location; throbbing pulsatile pain; nausea, vomiting, or abdominal pain; relief after sleep; and a family history of migraine.

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