PURLs
PURLs
Acute Achilles tendon rupture: Skip the surgery?
Nonoperative management for acute Achilles tendon rupture results in patient-reported outcomes similar to surgery at 1 year—but higher rates of...
PURLs
What BP target is appropriate for pregnant patients with mild chronic hypertension?
Active treatment to a lower blood pressure goal (< 140/90 mm Hg) can improve pregnancy outcomes without increasing maternal or fetal risk.
PURLs
Is combination pharmacotherapy effective for patients with acute depression?
A systematic review and meta-analysis found that these combinations were superior to monotherapy and had comparable tolerability.
PURLs
Is self-administered DMPA an answer to contraception access in the post-Roe era?
Compared with provider-administered depot medroxyprogesterone acetate, a prefilled formulation may offer patients improved access to effective...
PURLs
Consider this tool to reduce antibiotic-associated adverse events in patients with sepsis
Predictive biomarker procalcitonin can aid clinical decision-making on continued antibiotic treatment in this patient population.
PURLs
Put down the electronics after a concussion?
Yes, patients should do just that. In a randomized clinical trial, symptom duration was reduced when teens and young adults observed a certain...
PURLs
Consider this SGLT2 inhibitor for patients with HF with preserved ejection fraction
The addition of empagliflozin to usual therapy reduced hospitalization risk, regardless of patients’ diabetes status.
PURLs
Which anticoagulant is safest for frail elderly patients with nonvalvular A-fib?
In a retrospective study comparing direct oral anticoagulants vs warfarin in this population, apixaban’s adverse event rate was lower regardless...
PURLs
A “no-biopsy” approach to diagnosing celiac disease
This noninvasive alternative to the diagnostic gold standard may cut risk and expense for adult patients.
PURLs
Noncardiac inpatient has acute hypertension: Treat or not?
A retrospective study found more harm than benefit from treating elevated blood pressure in hospitalized noncardiac patients.
PURLs
Can early introduction of gluten reduce risk of celiac disease?
This UK study revealed the benefits of introducing gluten at age 4 months.