From the Journals

Lifetime risk of hand OA comes close to 40%


 

FROM ARTHRITIS & RHEUMATOLOGY

Almost 40% of Americans can expect to develop hand osteoarthritis (OA) in their lifetimes, according to an analysis involving participants from an ongoing population-based, prospective cohort study.

The overall risk, 39.8%, is based on data from 2,218 eligible subjects in the Johnston County Osteoarthritis Project, but there is significant variation among various subgroups, said Jin Qin, ScD, of the Centers for Disease Control and Prevention, and her associates (Arthritis Rheumatol. 2017 May 4. doi: 10.1002/art.40097).

Lifetime risk of symptomatic hand arthritis
Women have an estimated 47.2% lifetime risk – defined in the study as occurrence by age 85 years – of developing symptomatic hand OA, compared with 24.6% for men (P less than .0001). Whites have a 41.4% lifetime risk, compared with 29.2% for blacks (P = .031), the investigators reported, while those considered obese (body mass index of 30 kg/m2 or greater) have a risk of 47.1% and the nonobese have a risk of 36.1% (P = .063).

This report is the first to estimate the lifetime risk of symptomatic hand OA, they noted, and “given the aging population and increasing life expectancy in the United States, it is reasonable to expect that more Americans will be affected by this painful and debilitating condition in the years to come.”

The study was funded by the CDC and the National Institute of Arthritis and Musculoskeletal and Skin Diseases. The investigators did not include any disclosures in the report.

Recommended Reading

OA drug development needs patient-focused approach to biomarkers and outcome measures
MDedge Family Medicine
Thigh muscle weakness predicts knee osteoarthritis in women only
MDedge Family Medicine
Osteoarthritis in hip or knee can increase diabetes risk
MDedge Family Medicine
Rising arthritis prevalence driven by obesity
MDedge Family Medicine
CDC: Greater activity limitations accompany rising arthritis prevalence
MDedge Family Medicine
No benefit found for routine inpatient rehab after knee replacement
MDedge Family Medicine
Osteoarthritis’ link to metabolic syndrome tied to body weight, BMI
MDedge Family Medicine
Knee osteoarthritis linked to premature mortality
MDedge Family Medicine
Novel agent brings clinically meaningful improvements in knee osteoarthritis
MDedge Family Medicine
Adalimumab strikes out for hand osteoarthritis
MDedge Family Medicine