From the Journals

Possible increased breast cancer risk found in women with schizophrenia


 

FROM JAMA PSYCHIATRY


As it turns out, one of the subgroup analyses showed that the association between schizophrenia and breast cancer was significant only in studies that excluded women who were diagnosed with breast cancer before they were diagnosed with schizophrenia (standardized incidence ratio, 1.34; 95% CI, 1.20-1.51; P less than .001).

The same was seen in studies where there were more than 100 cases of breast cancer (SIR, 1.31; 95% CI, 1.18-1.46; P less than .001), while the association was not significant in studies with fewer than 100 cases.

The authors said their findings contradict a hypothesis that schizophrenia might be protective against cancer.

“These results, together with our recent meta-analysis results showing no association with lung cancer risk but a reduced hepatic cancer risk in schizophrenia, indicated that the association between schizophrenia and cancer risk may be complicated and depend on the cancer site,” wrote Dr. Zhuo and Dr. Triplett.

Recommended Reading

Schizophrenia patients’ mortality is 14.5 years shorter
MDedge Family Medicine
Seeing a doctor reduces readmission risk in schizophrenia patients
MDedge Family Medicine
Liraglutide produced cardiometabolic benefits in patients with schizophrenia
MDedge Family Medicine
VIDEO: What role does autoimmune dysfunction play in schizophrenia?
MDedge Family Medicine
Austedo approved for treatment of tardive dyskinesia
MDedge Family Medicine
Physical inactivity in youth is an independent risk factor for schizophrenia
MDedge Family Medicine
Psychotic symptoms predict persistent problems in adolescents
MDedge Family Medicine
Cannabidiol linked to reduction in psychotic symptoms in schizophrenia
MDedge Family Medicine
NIMH launches interactive statistics section on its website
MDedge Family Medicine
Watch for QTc interval prolongation in patients taking antipsychotics
MDedge Family Medicine