The researchers found no association between reported side effects and abnormal ECG, a positive personal history of cardiac problems, or a positive family history of cardiac problems.
Dr. Lund and her associates suggested that future revision of the guidelines should emphasize the absence of significant positive predictive value of ECG abnormalities for treatment-related side effects.
The researchers reported no relevant financial disclosures.
SOURCE: Lund EB et al. Ped Dermatol. 2018. doi: 10.1111/pde.13508.