The treated mice performed significantly better than the controls on a task that examined balance, general motor coordination, and functional integration. Their brains also showed 58% less tau pathology in the dentate gyrus of the hippocampus—an area important in memory.
Dr. Blennow's study was supported by Janssen Alzheimer Immunotherapy. Dr. Blennow had no relevant financial disclosures, but several of his coauthors are employees of Janssen, Pfizer, or Elan Pharmaceuticals, and own stock in the companies. Dr. Boche's study was sponsored by the Alzheimer's Research Trust; she and her coauthors reported having no financial disclosures. Dr. Boutajangout's study was sponsored by the Alzheimer's Association and Applied Neurosciences. Neither he nor his coauthors reported having any financial conflicts.