There remain many questions about effective chemopreventive therapy particularly regarding the length of therapy. Emerging data support continued risk reduction with persistent therapy.
Primary care practices have new tools to identify and manage patients at increased risk for breast cancer. Incorporation of the Gail model into the preventive care of selected women could identify patients at high risk for invasive breast cancer who would benefit from chemoprevention and possible multidisciplinary follow-up.
Dr. Anjali Sibley is assistant professor of medicine at Dartmouth Medical School and is in the department of hematology and oncology at Dartmouth Hitchcock Medical Center in Lebanon, N.H. Dr. William E. Golden is professor of medicine and public health at the University of Arkansas, Little Rock. Neither author reported having any conflicts of interest.