Photo Rounds

A new papule and “age spots”

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An 87-year-old woman came to the office for evaluation of a lesion above her lip (FIGURE 1) that had “been there a while” and had intermittently been bleeding and crusting for the last few months. On examination, there was a distinct, firm (but not hard) papule with some adjacent erythema. No distinct telangiectasias, ulceration, blood, or crusts were visible with handheld magnification or upon dermoscopy. (see The digital camera: Another stethoscope for the skin,”)

FIGURE 1
Lesion above lip

This lesion, which prompted the visit, had bled and crusted repeatedly in the past.

An evaluation of the remainder of the woman’s face revealed 3 more lesions that the patient termed “age spots.” They had been present for quite some time, had not had any notable rapid change, and had not caused her (or a physician in the family) any concern. These “age spots” are depicted in (FIGURE 2A) (left temple), (FIGURE 2B) (forehead), and (FIGURE 2C) (left cheek). Digital photographs were taken through the dermatoscope of the temple, forehead, and cheek lesions (FIGURE 3A, B, AND C).

FIGURE 2A
Digital photos

Temple: Asymptomatic papular “age spot” noted during examination of left temple near anterior to hairline.

FIGURE 2B
Digital photos

Forehead: Incidentally noted, asymptomatic, papular “age spot” on left forehead.

FIGURE 2C
Digital photos

Cheek: Incidentally noted, asymptomatic predominantly macular “age spot” on right cheek.

The 4 lesions are easily identified as worrisome, given that they were pigmented and asymmetric, with a variety of bizarre colors.

The lip. In particular, the lesion above the upper lip (FIGURE 1) clinically presented a wide range of possibilities, including basal cell carcinoma (BCC), milial cyst, nevus, trichoepithelioma, fibrous papule, or any of a variety of adnexal skin neoplasms. Knowing that the lesion was relatively new and had bled and crusted was sufficient to warrant biopsy.

The temple. Dermoscopically, the temple lesion (FIGURE 3A) had blue and brown ovoid structures (also called “blebs” or “blobs”), white areas within the lesion (whiter than normal surrounding skin), a high degree of asymmetry, and distinct telangiectatic vessels. The pink color on dermoscopy was also a cause for concern. The blue ovoid structures plus telangiectasias were highly suggestive of basal cell carcinoma.

FIGURE 3A
Dermoscopy images

Temple: Note telangiectatic vessels, blue and brown ovoid structures, pink and white areas, and hair protruding from the lesion at about 6 and 8 o’clock.

The forehead. Dermoscopy of the forehead lesion (FIGURE 3B) showed leaf-like structures (12 o’clock) and maple-leaf structures (6 o’clock). These alone were highly suggestive of pigmented basal cell carcinoma—but in the absence of distinct telangiectasias, we decided to do a deep incisional biopsy rather than risk potentially “shaving a melanoma.” (If a melanoma is biopsied via a shave technique, the ability to histologically measure its thickness and to stage it according to Clark and Breslow staging is lost.)

FIGURE 3B
Dermoscopy images

Forehead: Note leaf-like structure at 12 o’clock and above the periphery of the lesion at 6 o’clock. Also note blue and brown ovoid structures of varying sizes.

The cheek. Dermoscopically, the lesion on the cheek (FIGURE 3C) also had no obvious telangiectasias but had a “spoke-wheel” structure (6 o’clock) highly suggestive of basal cell carcinoma.

FIGURE 3C
Dermoscopy images

Cheek: “spoke-like” structure at 6 o’clock. Note the extensive variations in color and the asymmetry.

All the lesions—except for the temple lesion, which was biopsied via a shave technique—were biopsied via generous incisional ellipses.

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