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Sudden onset of amnesia in a healthy woman

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Our patient’s outcome

In the 24 hours after admission, the patient’s anterograde amnesia gradually resolved. She was able to remember the medical staff caring for her and retain orientation to her situation. However, she was unable to regain memories of the events immediately surrounding the onset of amnesia. During her hospitalization, the patient underwent a thorough work-up, including carotid artery Doppler ultrasound and echocardiogram with agitated saline (bubble study), both of which yielded normal results. Her MR angiography showed patent cerebral vessels. As mentioned, an MRI of the head showed a remote lacunar infarct of her left upper pons and nonspecific subcortical white matter disease was noted, consistent with chronic small vessel disease. The patient was discharged with reassurance, and she has done well.

CORRESPONDENCE
Chris Bernheisel, MD, director, Family Medicine Inpatient Service, The University of Cincinnati, 2123 Auburn Ave, Suite 340, Cincinnati, OH 45219; bernheiseljfp@me.com

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