Clinical Inquiries

Do intercontraction intervals predict when a woman at term should seek evaluation of labor?

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EVIDENCE-BASED ANSWER

NO; HOWEVER, A REDUCTION IN the intercontraction interval is associated with active labor (strength of recommendation [SOR]: B, cohort study).

Most primigravidas who have had regular contractions for 2 hours and multigravidas who have had regular contractions for 1 hour haven’t transitioned into the active phase of labor (SOR: B, cohort study).

Evidence summary

Multiple cohort studies demonstrate that the expected events of normal labor form a bell-shaped curve. The range of labor experiences makes predicting when a particular woman will enter active labor difficult.

When does latent labor become active labor?

The first stage of labor includes latent and active phases. The latent phase is defined as the period between onset of labor and cervical dilatation of 3 to 4 cm or the time between onset of regular contractions and escalation in the rate of cervical dilation. Regular contractions must be intense, last 60 seconds, and occur in a predictable pattern. Escalating cervical dilation is marked by a change in the cervical examination over a short period of time (usually 2 hours).1

The World Health Organization defines active labor as cervical dilation between 4 and 9 cm, with dilation usually occurring at 1 cm per hour or faster and accompanied by the beginning of fetal descent.2

Latent labor was initially described in a large prospective cohort of 10,293 term gravidas (including 4175 nulliparas and 5599 multiparas) followed from presentation to delivery.1 Cervical dilation was assessed by examination every 30 to 120 minutes, almost always performed by the same examiner throughout labor. In primigravidas, latent labor averaged 6.4 hours, with 95% of women completing the latent phase in 20.6 hours. In multigravidas, the mean duration of latent labor was 4.8 hours, with 95% of women transitioning to active labor in 13.6 hours.

Shorter intercontraction interval linked to active labor

A recently published cohort study of women presenting to labor and delivery found that a relative decrease in the intercontraction interval was associated with a diagnosis of labor (odds ratio=1.42; 95% confidence interval, 1.06-1.90). The study failed to define either active labor or decrease in the intercontraction interval.3

Earlier admission leads to more interventions and poorer outcomes

Many studies have suggested that admitting women to the hospital during the latent phase of labor is associated with more interventions and poorer outcomes. Two large retrospective cohort studies (N=2697 and 3220) found increased rates of cesarean section in women admitted during the latent phase.4,5 They also reported increased use of oxytocin, epidural analgesia, intrauterine pressure catheters, and fetal scalp electrodes, and increased rates of chorioamnionitis, postpartum infection, and neonatal intubation.4,5 See the TABLE for a summary of the effects of latent-phase admission.

TABLE
Consequences of hospital admission during latent vs active labor

NulliparousParous
ConsequenceLatent (%)Active (%)NNHLatent (%)Active (%)NNH
Oxytocin4 43276*2099*
Epidural4 82615*58406*
Assisted vaginal delivery4 2725508650
Cesarean4 10417*8650
Cesarean5 14714*3150*
pH <7.14 4310032100
Apgar <74 425032100
NNH, number needed to harm.
*Indicates relationship significant at the level <.05.
†Study by Bailit5 also showed significant associations for oxytocin, scalp pH, intrauterine pressure catheter, fetal scalp electrode, epidural, neonatal intubation, amnionitis, and postpartum infection. Raw data are unavailable for abstraction

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Evidence-based answers from the Family Physicians Inquiries Network

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