“Heart failure: Best options when ejection fraction is preserved” (J Fam Pract. 2013;62:236-243) was an excellent article about a tough problem. I have been using d-ribose for more than 5 years, with good results for both systolic and diastolic heart failure. D-ribose—which is made in the body from riboflavin found in many foods or can be purchased as an inexpensive supplement—has been cited in the literature for its beneficial effects.1,2
Art Sands, MD
Fort Collins, Colo