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"I don’t think we can consider these results definitive," she said. "Having said that, and with these caveats and recognizing the uncertainty, I would be comfortable offering goserelin to my young patients with estrogen receptor–negative breast cancer who desire to preserve fertility or prevent premature menopause."
The study was supported by the National Institutes of Health. Dr. Moore reported no disclosures; three coauthors have financial ties with AstraZeneca, maker of goserelin. Dr. Giordano reported no relevant disclosures.