Dermatology
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What are the clinical implications of recent skin dysbiosis discoveries?
Activities that can contribute to alterations in skin flora or skin dysbiosis include topical application of steroids, antibiotics, retinoids,...
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Painful axillary lesions
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Penile rash
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Analysis identifies gaps in CV risk screening of patients with psoriasis
Regional variation in screening rates “is not explained by patient demographics or disease severity.”
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Frustration over iPLEDGE evident at FDA meeting
Dermatologists argue the iPLEDGE REMS burden is too high for providers and patients. Access problems persist with lockouts and some cite a lack of...
Feature
Biosimilars and patients: Discussions should address safety, cost, and anxiety about change
Physicians can respond to pushback from patients on switching to a biosimilar by offering resources and discussing options for both biosimilar and...
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FDA panels vote to modify isotretinoin iPLEDGE REMS
The committees sought to balance reducing burden with maintaining safety and preventing fetal exposures to isotretinoin.
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Limited treatment options exist for brittle nail syndrome
“It’s our duty to warn our patients about the evidence for biotin for treating brittle nails, and about this interference on laboratory tests,” Dr...
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FDA Advisory panels consider easing isotretinoin requirements
The 2-day meeting is addressing what can be done to reduce burden with the iPLEDGE REMS while maintaining safety and preventing fetal exposure to...
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JAK inhibitor ivarmacitinib shows efficacy for atopic dermatitis in a pivotal trial
The co-primary endpoints were change in IGA and EASI scores at 16 weeks, and both improved rapidly, showing statistical significance relative to...
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Topical delgocitinib shows promise for chronic hand eczema, pivotal trial shows
Delgocitinib is an investigational topical pan-JAK inhibitor that inhibits activation of the JAK-STAT pathway.