Rare Diseases
Case Reports
Lack of energy, petechiae, elevated PSA level—Dx?
News
Paradigm shift: Prophylactic salpingectomy for ovarian cancer risk reduction
Photo Rounds
Hands with erythematous patches
A 49-year-old Caucasian man sought care for erythematous patches on the dorsal surface of his hands that he’d had for 2 to 3 years. These patches...
Conference Coverage
Autism sibling studies beginning to yield data
Commentary
ALS ice bucket challenge: It’s hard to argue with success
News
New Creutzfeldt-Jakob disease tests have high sensitivities, specificities
Key clinical point: Two minimally invasive approaches to detecting misfolded prion proteins have high sensitivities and specificities for...
Photo Rounds
Cutaneous eruption on chest and back
The cause of this “dirty” rash was fairly obvious to us, but only because we’d encountered this rare skin disorder before.
Photo Rounds
Copper ring around cornea
News
Novel antimetabolite strategy slows progression of deadly mesothelioma
Key clinical point: An antimetabolite strategy that cuts off the supply of arginine to tumors may benefit patients with mesothelioma.Major finding...
Conference Coverage
Dissociation found to mediate ketamine’s antidepressive effects
Key clinical point: Some degree of dissociation might be needed "as a proxy for the strength of the NMDA receptor blockade because of its...
Conference Coverage
Lurasidone monotherapy improves quality of life in bipolar I
Key clinical point: Lurasidone appears to reduce depressive symptoms in patients with bipolar I depression without the metabolic complications...