ALL
News
Discovery could change management of ALL
Two genes appear to play a key role in acute lymphoblastic leukemia (ALL), particularly for patients who also have Down syndrome. Researchers...
News
CAR T-cell therapy gets breakthrough designation
The US Food and Drug Administration (FDA) has granted breakthrough therapy designation for the T-cell therapy CTL019 to treat adults and children...
Conference Coverage
Phase 2 results lead to breakthrough designation
The decision was based on promising results of a phase 2 trial, which were presented at the 50th Annual Meeting of the American Society of...
News
Long-term complications after ALL minimal, study shows
Credit: Bill Branson Children recently diagnosed with standard-risk acute lymphoblastic leukemia (ALL) are likely to have few long-term...
News
Restoring gene function can ‘reverse’ B-ALL
and Ross Dickins, PhD Credit: Walter and Eliza Hall Institute of Medical Research Results of preclinical research suggest B-progenitor acute...
News
Defect promotes CNS invasion of ALL in mice
Credit: Aaron Logan Researchers say they’ve uncovered a genetic defect in acute lymphoblastic leukemia (ALL) cells that promotes their invasion...
News
One in four children with ALL misses maintenance doses
Credit: Bill Branson Forgetting to take medication is the number one reason for non-adherence to maintenance therapy in children with acute...
News
Monoclonal antibody could improve treatment of ALL
Credit: Linda Bartlett Preclinical research suggests the B-cell activating receptor (BAFF-R) may be a promising therapeutic target for treatment-...
News
MRD test can predict HSCT outcomes in ALL patients
Credit: Graham Colm A method of measuring minimal residual disease (MRD) can predict transplant outcomes in adults with acute lymphoblastic...
News
FDA approves new formulation of mercaptopurine
Credit: Bill Branson The US Food and Drug Administration (FDA) has approved an oral suspension of mercaptopurine (Purixan), a drug used in...
Conference Coverage
Leukemic breast tumors may cause resistance in AML, ALL
Isabel Cunningham, MD, of Columbia University in New York, has found evidence to suggest that treatment resistance in leukemia patients may...