ALL
News
FDA lifts clinical hold on CAR T-cell study
Credit: MSKCC The US Food and Drug Administration (FDA) has lifted a clinical hold placed on a trial of chimeric antigen receptor (CAR) T-cell...
News
Explaining the link between Down syndrome and B-ALL
Credit: Aaron Logan Investigators believe they’ve uncovered information that explains the connection between Down syndrome and B-cell acute...
Conference Coverage
Enrollment stalled for CAR T-cell study
Memorial Sloan-Kettering Cancer Center has temporarily suspended enrollment in a study of chimeric antigen receptor (CAR) T-cell therapy, due to 2...
News
ALL cells don’t survive SSC culture method
Results of a pilot study suggest safe transplantation of spermatogonial stem cells (SSCs) may be possible, potentially bringing us one step closer...
News
Abnormality increases risk of ALL subtype
Credit: Beth A.
News
ALL maintenance phase still stressful, studies show
Credit: Bill Branson The stress and lifestyle changes mothers experience after a child’s leukemia diagnosis do not disappear once the disease is...
News
Targeting pathways can override resistance in ALL
Inhibiting two biosynthesis pathways can override treatment resistance in acute lymphoblastic leukemia (ALL), preclinical research suggests....
News
Investigating the cause of infant leukemias
Results of whole-exome sequencing suggested that infants with leukemia inherited genetic variants from both parents that, by themselves, would not...
News
Research clarifies role of Ikaros in B-ALL
Credit: Aaron Logan Two papers published in Nature Immunology have shed new light on the role of Ikaros in B-cell acute lymphoblastic leukemia (B...
News
Combo may overcome drug resistance in ALL
Credit: Linda Bartlett Adding the alkylating agent cyclophosphamide to treatment with a monoclonal antibody (mAb) can overcome drug resistance in...
News
Ponatinib back on the market
Ariad Pharmaceuticals, Inc., has begun shipping the drug to Biologics, Inc., its exclusive specialty pharmacy.