Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

HSCT performs well in scleroderma-related lung disease

Goldin J et al. Arthritis Rheumatol. 2018;70(Suppl 10): Abstract 901

Key clinical point: Lung CT scores remain stable or improve following hematopoietic stem cell transplantation in patients with scleroderma-related interstitial lung disease when compared against monthly cyclophosphamide treatments.

Major finding: Quantitative interstitial lung disease scores decreased by 7% at 54 months in hematopoietic stem cell transplant patients versus no change in those who received cyclophosphamide (P = .024).

Study details: A study of 75 patients from the SCOT trial.

Disclosures: The investigators reported having no relevant disclosures.

Read the article here.

Citation:

Goldin J et al. Arthritis Rheumatol. 2018;70(Suppl 10): Abstract 901.