Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Statins may affect prostate cancer microenvironment
Allott E et al. AUA 2018 (annual meeting of the American Urological Association), Abstract MP21-01.
Key clinical point: Researchers hope that genetic analyses could eventually point to prostate cancer patients who might benefit from statin use.
Major finding: Long-term statin users had lower odds of having a pTEN-null tumor (hazard ratio, 0.42), which is associated with worse outcomes.
Study details: Retrospective analysis of 5,792 diagnoses of prostate cancer among 44,076 men.
Disclosures: The study was funded by the Irish Cancer Society, the John Fitzpatrick Fellowship, and the National Cancer Institute. Dr. Allott reported no relevant financial relationships.
Source: Allott E et al. AUA 2018, Abstract MP21-01.
Allott E et al. AUA 2018 (annual meeting of the American Urological Association), Abstract MP21-01.