Key clinical point: Relative to conventional photon radiotherapy, proton beam radiotherapy for locally advanced non–small cell lung cancer may reduce cardiovascular events.

Major finding: Proton beam radiotherapy, as compared with photon radiotherapy, was associated with a significantly lower incidence of transient ischemic attack (1.1% vs. 8.2%; P = .04) and a trend toward a lower incidence of MI (2.3% vs. 9.0%; P = .06).

Study details: A single-center, retrospective study of 202 consecutive patients given chemotherapy and photon (n = 104) or proton beam (n = 98) radiotherapy for locally advanced non–small cell lung cancer.

Disclosures: The study did not receive specific funding. Dr. Kegelman disclosed no relevant conflicts of interest.