Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Sleep quality linked to cognitive decline in older breast cancer survivors

Publish date:: October 8, 2019

Key clinical point: Sleep disturbance and gene interactions could increase the risk of cognitive decline and dementia among older breast cancer survivors.
Major finding: When experiencing sleep disturbances, patients who carried the APOE gene had significantly worse learning and memory performance than noncarriers (P = .001).
Study details: An observational study involving 319 women with breast cancer who were 60 years or older.
Disclosures: The study was funded by the National Cancer Institute and the American Cancer Society. The investigators reported additional relationships with Amgen, Seattle Genetics, AstraZeneca, and others.

Citation:

Carroll et al. Cancer. 2019 Sept 25. doi: 10.1002/cncr.32489.

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