CML
From the Journals
Secondary reference panel expands access for CML monitoring
A cell-based BCR-ABL1 secondary reference panel traceable to the World Health Organization BCR-ABL1 International Genetic Reference Panel – with...
News
Two-drug combination targets LSCs in CML
Image by Difu Wu Targeting a pair of transcription factors might improve the treatment of chronic myeloid leukemia (CML), according to...
News
Compound could treat a range of blood cancers
Image by Ed Uthman A new compound has shown promise for treating hematologic malignancies and other cancers, according to preclinical research...
News
Legislators question price of leukemia drug
Photo from Business Wire A pair of US legislators are questioning why ARIAD Pharmaceuticals, Inc. has increased the price of its leukemia drug...
From the Journals
STIM1 long-term follow-up confirms imatinib discontinuation safety
Imatinib discontinuation is safe in patients with chronic myeloid leukemia who have sustained deep molecular response with no late molecular...
From the Journals
Cost may hinder timely TKI initiation for CML
Nearly a third of Medicare beneficiaries with chronic myeloid leukemia did not initiate tyrosine kinase inhibitor therapy within 6 months of...
Conference Coverage
Doc offers advice on choosing a frontline TKI
Photo by D.
News
Medicare doesn’t lower TKI costs enough, study suggests
cut in half with a pill splitter Photo by Patrick Pelletier Significant out-of-pocket costs may delay treatment for Medicare beneficiaries with...
News
Ponatinib approved to treat CML, ALL in Japan
Image from UCSD The Japanese Pharmaceuticals and Medical Devices Agency (PMDA) has approved 2 uses of the tyrosine kinase inhibitor (TKI)...
News
DNA methylation rises sharply at progression of Ph+ CML
Key clinical point: Increases in DNA methylation occur at progression of Ph+ CML; this realization may enable new therapeutic targets. Major...
News
EZH2 inhibitors could improve treatment of CML, studies suggest
Image by Difu Wu Two preclinical studies published in Cancer Discovery suggest that EZH2 inhibitors might enhance the efficacy of treatment with...