CML
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New anticancer drugs linked to increased costs, life expectancy
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Combo could provide cure for CML, team says
Preclinical research suggests that combining a BCL2 inhibitor with a BCR-ABL tyrosine kinase inhibitor (TKI) can eradicate leukemia stem cells (...
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NICE approves bosutinib for routine NHS use
The National Institute for Health and Care Excellence (NICE) has issued a final guidance recommending that bosutinib (Bosulif), a tyrosine kinase...
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Teva launches generic imatinib tablets in US
Photo by Steven Harbour Teva Pharmaceutical Industries Ltd.
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FDA clears kit for monitoring molecular response in CML
Photo by Juan D.
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Study may explain how LSCs evade treatment
Image by Robert Paulson New research suggests leukemia stem cells (LSCs) can “hide” in gonadal adipose tissue (GAT) and transform the tissue so...
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Treatment-free remissions achieved in patients with chronic myeloid leukemia
Key clinical point: Treatment-free remission attempts are safe and are achievable in most patients with chronic myeloid leukemia in chronic phase...
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Cancer cell lines predict drug response, study shows
Image from PNAS A study published in Cell has shown that patient-derived cancer cell lines harbor most of the same genetic changes found in...
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NICE recommends approval for bosutinib
Photo courtesy of CDC The National Institute for Health and Care Excellence (NICE) has issued a final draft guidance recommending approval for...
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Drugs produce comparable results in CP-CML
Long-term results from the DASISION trial suggest that dasatinib and imatinib produce similar outcomes in patients with newly diagnosed chronic...
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Study: CMV doesn’t lower risk of relapse, death
Small studies have suggested that early cytomegalovirus (CMV) reactivation may protect against leukemia relapse and even death after hematopoietic...