CML
News
Team describes method of targeting LSCs in BC-CML
Photo courtesy of UC San Diego Health New research has revealed a method of targeting leukemia stem cells (LSCs) in blast crisis chronic myeloid...
Conference Coverage
Stopping TKI therapy can be safe, study suggests
COPENHAGEN—Results of a large study suggest that stopping treatment with tyrosine kinase inhibitors (TKIs) can be safe for patients with chronic...
News
How CML cells respond to stress
Image by Difu Wu Researchers have used a tiny force probe to compare how healthy hematopoietic cells and cancerous ones respond to stress. They...
Conference Coverage
Hold that TKI – When it’s safe to stop in CML
Key clinical point:.Tyrosine kinase inhibitor therapy can be safely stopped and resumed in many patients with chronic-phase chronic myeloid...
News
Tyrosine kinase inhibitors may boost cardiac risk in chronic myeloid leukemia
Tyrosine kinase inhibitors were associated with a significantly increased risk of cardiovascular events among chronic myeloid leukemia patients....
Conference Coverage
Most CML patients who stop nilotinib stay in remission
CHICAGO—Nearly 60% of chronic myeloid leukemia (CML) patients who switch to nilotinib from imatinib maintain treatment-free remission for 48 weeks...
Conference Coverage
Dr. Matt Kalaycio’s top 10 hematologic oncology abstracts for ASCO 2016
News
Dasatinib bests imatinib on molecular, cytogenic response rates in CML
Key clinical point: Patients with chronic myeloid leukemia who received dasatinib experienced higher rates of major molecular response and...
News
CML: T3151 plus additional mutations predicts poor response to ponatinib
Key clinical point: The third-generation tyrosine kinase inhibitor ponatinib appears to be more effective than its predecessors against certain...
News
VP Biden to AACR: Help me help you
Strengthening teamwork among researchers, sharing data, and realigning incentives for scientific breakthroughs are top strategies to advance...
News
Model used to estimate CSCs in CML
Image from UC San Diego Scientists say they have developed a model that can be used to calculate the proportion of cancer stem cells (CSCs)...