Melanoma
Conference Coverage
Cases of pediatric invasive melanoma have declined since 2002, study finds
AUSTIN – Further studies are required to investigate the contributing factors to decreasing incidence.
Conference Coverage
IL-6, CRP are prognostic for checkpoint inhibition in melanoma
CHICAGO – Post hoc analyses show that baseline and on-treatment C-reactive protein and interleuken-6 levels are prognostic for checkpoint...
Latest News
Another study supports safety of 2-cm margins for thick melanomas
Similar outcomes seen with 4-cm and 2-cm excision margins for melanomas greater than 2 mm.
Conference Coverage
Novel immune checkpoint holds ‘great promise’ as melanoma treatment target
MILAN – A monoclonal antibody directed against DC-HIL reduced melanoma growth and metastasis in animal models.
Conference Coverage
Entrectinib exhibits activity in children with solid tumors
Entrectinib produced responses in patients who had fusions or mutations in target genes.
Clinical Review
Advanced Melanoma: Treatment After Progression on First-line Therapy
From the Journals
Patients lack confidence in their skin self-exam abilities
While most patients were willing to use teledermoscopy to assist them in self-exams, they still preferred to rely on regularly scheduled physician...
Clinical Review
Advanced Melanoma: First-line Therapy
From the Journals
Systemic therapies are impacting melanoma’s prognostic factors
Systemic treatments have altered the disease kinetics for patients with melanoma.
Conference Coverage
ENCORE-601: Entinostat/pembrolizumab safe, active for melanoma
ATLANTA – Combined therapy with the HDAC inhibitor entinostat and the PD-1 inhibitor pembrolizumab has significant clinical activity and...
Conference Coverage
Consider 9-mm surgical margins for MIS
WAIKOLOA, HAWAII – The widely utilized 5-mm surgical margins for excision of melanoma in situ are inadequate.