Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Must Reads by Date

Must reads for theWeek ending March 24, 2019

PEs Nearly Doubled During 2004-2015,

Increased sudden death risk in HIV linked to cardiac fibrosis,

BP control slowed brain damage in elderly hypertensives,

Physician Groups Produce More Accurate Diagnoses than Individuals,

Abstinence by moderate drinkers improves their AFib,

More must reads

Must reads for theWeek ending March 17, 2019

Antibiotic-eluting envelope reduces CIED infections,

Apple Watch algorithm showed 84% positive predictive value for Afib,

CREOLE: Amlodipine may be preferable for lowering blood pressure in black patients,

Immediate angiography after non-STEMI cardiac arrest confers no survival benefit,

Repeat VTE risk heightened in HIV patients,

More must reads

Must reads for theWeek ending March 10, 2019

Evaluations for Possible MS Often Turn up One of its Many Mimics,

Low-Risk TAVR Trial Shows Low Mortality at 1 Year,

In utero infections raise risk for autism,

Alcohol-Mediated Renal Denervation Appears Safe for BP Reduction,

Anxiety, Depression Compromise Believability of Drug-Allergy Testing,

More must reads

Must reads for theWeek ending March 3, 2019

Biologic aging is associated with MS disability progression,

Novel capsid assembly modulator shows promise in HBV,

Large survey reveals that few MS patients have long-term care insurance,

Myeloma therapies raise cardiovascular risks,

Sperm counts largely stable after adjuvant treatment of clinical stage I testicular cancer,

More must reads

Must reads for theWeek ending February 24, 2019

Smoking cessation could delay or prevent rheumatoid arthritis,

Alcohol abstinence questioned as addiction treatment goal, AAAP 2018

TNF inhibitor prices rose despite increased drug class competition, San-Juan-Rodriguez A et al. JAMA Intern Med. 2019 Feb 18. doi: 10.1001/jamainternmed.2018.7656

List of medications linked to drug-induced lupus expands, Arnaud L et al. Ann Rheum Dis. 2019 Feb 4. doi: 10.1136/annrheumdis-2018-214598

HCV-infected patients in the ED should be tested for advanced liver fibrosis, Yu-Hsiang Hsieh Y-H. Am J Emerg Med. 2019;37[2]:286-90
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