Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Altering gut microbiome may reduce tumor-promoting effects of smoking

Key clinical point: Altering the gut microbiome may reduce the tumor-promoting effects of cigarette smoking.

Major finding: Mice treated with microbiome-depleting antibiotics and exposed to smoke had significantly lower rates of cancer growth than mice not treated with antibiotics and exposed to smoke (P < .001).

Study details: A mouse model study involving wild-type and genetically engineered mice.

Disclosures: The study was funded by the Florida Department of Health. The investigators reported no conflicts of interest.

Citation:

Sharma P et al. DDW 2020.