Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Must Reads by Date

Must reads for theWeek ending November 22, 2015

Cognitive Decline in Multiple Sclerosis, Assessing the effects of thalamus atrophy

Detecting Autoantibodies in Multiple Sclerosis, Evaluating the use of electrochemiluminescence assay

Cerebellar Growth in CNS Demyelinating Disease, Does age of onset correlate with volume loss?

Teriflunomide in Relapsing-Remitting MS, Comparing adverse events across studies

Escalation of Therapy in Neuromyelitis Optica Attacks, Do multiple courses of treatment affect outcomes?

More must reads

Must reads for theWeek ending November 15, 2015

HRQOL Following Minor Ischemic Events, Predicting impairment at 3 months

Neurofilament Light Concentration in Alzheimer Disease, Studying associations with cognitive deterioration

Cerebral Amyloid Angiopathy in AD, Defining cognitive associations

Narcolepsy in African Americans, Does ethnicity affect sleep patterns?

Curative Surgery for Epileptic Spasms, Which procedures produce the best outcomes?

More must reads

Must reads for theWeek ending November 8, 2015

Progressive Multifocal Leukoencephalopathy in MS, Evaluating the role of John Cunningham virus

Soluble CD26 and CD30 in MS, Assessing associations with immune responses

Alemtuzumab in Relapsing MS, Does clinical trial data hold up?

Cardiac Events in Fingolimod Initiation, Evaluating events in 850 episodes

Associations Between Symptoms, Community Integration, and Mental Health, Does MS type or level of progression define the patient?

More must reads

Must reads for theWeek ending November 1, 2015

Mild Traumatic Brain Injury and PTSD, Does it have prognostic value?

Brivaracetam and Partial-Onset Seizures, Studying efficacy and tolerance

PTSD in Patients With Migraine, Assessing the impact

Sleep Apnea and Cardiovascular Surgery, Does it affect outcomes?

Imaging Assessments vs Outcomes in Stroke, Evaluating mismatch profiles

More must reads

Must reads for theWeek ending October 25, 2015

Oligoclonal Bands and Multiple Sclerosis, Assessing their significance in patients with CIS

Cladribine in Multiple Sclerosis, Does it confer cancer risk?

MOG-Ab in Inflammatory Demyelinating Disease, Evaluating its utility as biomarker

Vitamin D and Multiple Sclerosis, Studying associations with regulatory variants

Statins in RRMS Therapy, Is there benefit to their addition?

More must reads

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