Depression
News
Biomarkers Linked to L-Methylfolate Effectiveness for Depression
News
Opioid-Like Drug Limited Recalcitrant Major Depression
Major Finding: ALKS 5461 showed rapid efficacy in 32 patients with major depressive disorder who failed to respond adequately to treatment with...
News
Levomilnacipran SR Effective for Major Depressive Disorder
Major Finding: On the Montgomery-Asberg Depression Rating Scale–Clinician Rated, the least-squares mean difference versus placebo for total score...
News
Weight Gain Low, Comparable to Placebo in Vilazodone Trial
Major Finding: The least squares mean differences for change from baseline in MADRS in each severity group was significantly better for vilazodone...
News
Exercise Reaps Double Benefits in Post-MI Depression
News
Phone Therapy for Depression Boosts Treatment Adherence
Major Finding: Significantly fewer depression patients discontinued cognitive behavior therapy when treated by phone vs. in-person treatment (21%...
Commentary
Treating resistant depression
News
Vilazodone Found Effective Across Depression Symptoms
Major Finding: Compared with 432 patients who received placebo, the 431 patients randomized to receive vilazodone experienced significant...
Podcasts
Mimics of depression
Sandra Rackley, MD
Evidence-Based Reviews
Recognizing mimics of depression: The ‘8 Ds’
This mnemonic helps recall conditions that may make medically ill patients appear depressed
From the Editor
Innovative approaches to treatment-resistant depression
Emerging paradigm shifts are reconceptualizing the causes and treatments of severe depression