Schizophrenia & Other Psychotic Disorders
From the Journals
Antipsychotic effective for bipolar depression in phase 3 trial
At day 43, lumateperone treatment was associated with significantly greater improvement from baseline in the MADRS score, compared with placebo....
From the Journals
Gut health ‘vitally important’ for mental health
“It’s clear that clinicians need to place a greater awareness of gut health when considering the treatment of certain psychiatric disorders.”
Feature
The role of probiotics in mental health
The evidence for the effects of probiotics so far is the strongest for depression, says Viktoriya Nikolova, of Kings College London.
From the Journals
Antipsychotics tied to increased breast cancer risk
“Inform patients about a potential risk to allow for informed shared decision-making,” said study coauthor Dr. Christoph U. Correll.
From the Journals
Optimal antipsychotic dose for schizophrenia relapse identified
“The safest approach is to just to carry on with 5 mg,” which in many cases represents a full dose, said lead author Dr. Stefan Leucht.
FDA/CDC
FDA approves first twice-yearly antipsychotic for schizophrenia
The approval is based on results from a 12-month, randomized, double-blind, phase 3 study that enrolled 702 adults with schizophrenia from 20...
Pearls
Conspiracy theory or delusion? 3 questions to tell them apart
Many psychiatrists conceptualize mental illnesses, including psychotic disorders, across a continuum where their borders can be ambiguous.
Cases That Test Your Skills
An unquenchable thirst
Mr. F, age 44, has schizophrenia that includes religious delusions. After a presumed seizure and fall, he develops delirium. What’s causing these...
Conference Coverage
Neurodegenerative nature of schizophrenia makes case for LAIs
Switching patients to long-acting injectables upon discharge from the first episode "astonishingly is rarely done by 99% of clinicians," said Dr....
Conference Coverage
Nonmotor symptoms common in Parkinson’s
Neuropsychiatric symptoms often go unrecognized, but they are treatable, said Dr. Leslie Citrome.
From the Journals
Psychotic features among older adults tied to Parkinson’s
New-onset psychosis was associated with a fivefold increased risk of both subthreshold parkinsonism and depression, Dr. Ioanna Pachi reported.