Schizophrenia & Other Psychotic Disorders
Pearls
Treating psychosis in pregnant women: A measured approach
The peak age of onset of schizophrenia coincides with the peak childbearing age of 25 to 35 years.
Conference Coverage
Long-acting injectable antipsychotics deserve first-line consideration
Circumventing large risks of nonadherence, long-acting injectables should be an option considered routinely, said Dr. Diana Perkins.
Conference Coverage
Emerging drugs for schizophrenia targeting negative symptoms
Several antipsychotics that show efficacy against negative symptoms are in advanced stages of development, said Dr. Henry A. Nasrallah.
Feature
How a community-based program for SMI pivoted during the pandemic
Fountain House now faces new challenges operating as a possible hybrid model, Dr. Ashwin Vasan said.
From the Journals
Cortical thinning in adolescence ‘definitively’ tied to subsequent psychosis
"This is the first study to definitively show that there are subtle, widespread structural brain differences in high-risk youth before they...
From the Journals
Schizophrenia meds a key contributor to cognitive impairment
The investigators found that 63% of participants had an anticholinergic cognitive burden score of at least 3, which is "striking."
Conference Coverage
Once-weekly oral antipsychotic for schizophrenia on the horizon
LYN-005 was well tolerated in the 85% of study participants who received all three doses.
From the Journals
Emotional support animals help lick symptoms of depression, anxiety in serious mental illness
“There is definitely a place for ESAs, especially with mental health post pandemic,” said Dr. Janet Hoy-Gerlach.
FDA/CDC
FDA okays new drug option for schizophrenia, bipolar I disorder
The FDA approved Lybalvi under the 505(b)(2) regulatory pathway based on data from 27 clinical studies.
Med/Psych Update
Ketamine for acute catatonia: A case report
Our patient’s experience suggests this agent might reduce mutism and immobility.
Savvy Psychopharmacology
Efficacy and safety of high-dose antipsychotic therapy
Mr. K, age 21, is admitted to the psychiatry unit with agitation, disorganized behavior, and paranoia. Upon presentation, he has no known medical...