Somatic Disorders

Savvy Psychopharmacology

Managing clozapine-induced neutropenia and agranulocytosis

Author:

Jeremy S. Daniel, PharmD, BCPS, BCPP

Tonya Gross, PharmD

Mr. S, age 43, has schizophrenia and been stable on clozapine for 6 years after several other antipsychotic regimens failed. Mr. S also has a...

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Med/Psych Update

How to assess and manage high cholesterol in patients with mental illness

Author:

Erik R. Vanderlip, MD, MPH

Statins, lifestyle changes could reduce total cholesterol and cardiovascular risk High serum cholesterol is a leading cause of heart attack and...

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Pearls

Assess and treat catatonia using this systematic approach

Author:

Brian Holoyda, MD

Glen Xiong, MD

Catatonia is a neuropsychiatric condition with varying presentations that involve behavioral, motoric, cognitive, affective, and, occasionally,...

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Pearls

Consider Rx metformin to prevent metabolic syndrome

Author:

Adrienne T. Gerken, MD

Travis P. Baggett, MD, MPH

Oliver Freudenreich

MD

Many atypical antipsychotics, particularly clozapine and olanzapine, are associated with weight gain, insulin resistance, and metabolic syndrome....

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Med/Psych Update

High-value intervention: Providing colorectal cancer screening

Author:

Jaesu Han, MD

Cerrone Cohen, MD

Cancer screening is an important example of secondary prevention—the aim being to detect disease at an early stage, when treatment can prevent...

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Pearls

Take steps to relieve ataxia in patients with alcohol use disorder

Author:

Daniel Lache, MD

Vasant Dhopesh, MD

Ataxia is a well-known complication of chronic alcohol abuse, which is attributed to degeneration of the cerebellar vermis. However, effective...

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Video

Ataxia due to alcohol abuse

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Out Of The Pipeline

Pimavanserin for psychosis in patients with Parkinson’s disease

Author:

Jonathan M. Meyer, MD

Pimavanserin is a potent 5-HT2A inverse agonist and 5-HT2C inverse agonist, with 5-fold greater affinity for the 5-HT2A receptor.¹...

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Cases That Test Your Skills

Pregnant nearly a year? The patient has symptoms but evidence is lacking

Author:

Andrew C. Buchholz, DO, MPH

Paul Bell, MD

Brandon Schabecker, MD

Janet Arnold, MD

John A. Van Skyle, DO, DFAPA

Hamid R. Tavakoli, MD

Mrs. X, age 43, reports that she has been pregnant for 11 months. Pregnancy tests and transvaginal ultrasonography are negative. She has no...

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Evidence-Based Reviews

Pseudobulbar affect: When patients laugh or cry, but don’t know why

Author:

Benjamin Frock, MD

Andrew Williams, MD

Jason P. Caplan, MD

Pseudobulbar affect (PBA) is a disorder of affective expression that manifests as stereotyped and frequent outbursts of crying (not limited to...

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Podcasts

Adjusting the dosing of antipsychotics and other psychotropics in renal disease

Author:

William J. Resch, DO, DFAPA

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